Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/5/2025

Improving Nasal Comfort with Air Nasal Pillows for PAP Therapy

Proper Mask Selection and Fitting

  • The American Academy of Sleep Medicine recommends ensuring proper mask fit by testing the seal under treatment pressure before beginning therapy, as poor fit is a primary cause of discomfort 1, 3
  • Mask refit or adjustment should be performed whenever significant unintentional leak is observed or when experiencing discomfort, as suggested by the American Academy of Sleep Medicine 4, 5

Humidification Optimization

  • The American Academy of Sleep Medicine suggests adding heated humidification to your PAP device if not already using it, as this significantly reduces nasal dryness, congestion, and discomfort 2, 6
  • Higher PAP pressures reduce relative humidity of delivered air, requiring higher humidification settings, according to the American Academy of Sleep Medicine 1, 7
  • Cleaning the humidifier chamber regularly is recommended to prevent mineral buildup that can affect performance, as stated by the American Academy of Sleep Medicine 2

Managing Air Leaks

  • Unintentional mask leaks, particularly mouth leaks when using nasal pillows, are a major cause of nasal discomfort, and using a chin strap to keep the mouth closed can help, as suggested by the American Academy of Sleep Medicine 4, 3
  • If mouth breathing persists despite using a chin strap, considering switching to a full-face mask may be necessary, according to the American Academy of Sleep Medicine 4, 5

Pressure Setting Adjustments

  • The American Academy of Sleep Medicine recommends considering using pressure relief features (flexible PAP) that lower pressure during exhalation if experiencing discomfort during exhalation 4, 8
  • Adjusting rise time (duration for pressure change from EPAP to IPAP) for comfort, with shorter rise times (100-400ms) often working better for obstructive airway disease, is suggested by the American Academy of Sleep Medicine 4

Additional Comfort Measures

  • Elevating the head of the bed can help if experiencing difficulty tolerating prescribed pressure, as recommended by the American Academy of Sleep Medicine 4
  • If persistent nasal symptoms occur despite other measures, consulting a healthcare provider about prescription nasal sprays is suggested by the American Academy of Sleep Medicine 2

Common Pitfalls to Avoid

  • The American Academy of Sleep Medicine advises against assuming dry mouth or nasal discomfort is normal with PAP therapy, as these often indicate correctable issues 5
  • Focusing only on mask type while ignoring humidification and pressure settings should be avoided, as stated by the American Academy of Sleep Medicine 5

REFERENCES

1

best clinical practices for the sleep center adjustment of noninvasive positive pressure ventilation (nppv) in stable chronic alveolar hypoventilation syndromes. [LINK]

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2010

2

clinical guidelines for the manual titration of positive airway pressure in patients with obstructive sleep apnea. [LINK]

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2008

3

best clinical practices for the sleep center adjustment of noninvasive positive pressure ventilation (nppv) in stable chronic alveolar hypoventilation syndromes. [LINK]

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2010

4

Management of Sudden Onset Dry Mouth with PAP Therapy [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

5

treatment of adult obstructive sleep apnea with positive airway pressure: an american academy of sleep medicine clinical practice guideline. [LINK]

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019

6

treatment of adult obstructive sleep apnea with positive airway pressure: an american academy of sleep medicine clinical practice guideline. [LINK]

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019

7

best clinical practices for the sleep center adjustment of noninvasive positive pressure ventilation (nppv) in stable chronic alveolar hypoventilation syndromes. [LINK]

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2010

8

treatment of adult obstructive sleep apnea with positive airway pressure: an american academy of sleep medicine clinical practice guideline. [LINK]

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019