Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/29/2025

Botulinum Toxin for Cerebral Palsy Spasticity Management

Evidence Supporting Medical Necessity

  • Targeted injection of botulinum toxin into localized lower limb muscles is recommended to reduce spasticity that interferes with gait function in cerebral palsy patients 1
  • Botulinum toxin is effective for treating lower limb spasticity in adults and improving passive function (improved range of motion) 3
  • Chemo-denervation using botulinum toxin can be used to increase range of motion and decrease pain for patients with focal symptomatically distressing spasticity in both upper and lower limbs 4

Specific Application to This Case

  • The American Heart Association/American Stroke Association recommends targeted botulinum toxin injections for spasticity management in patients with cerebral palsy, such as the patient with right-sided hemiplegic cerebral palsy 1, 2

Treatment Algorithm

  • Confirm diagnosis of spasticity related to cerebral palsy, and administer targeted botulinum toxin injections to affected muscles, as recommended by the American Heart Association/American Stroke Association 1