Treatment of Duodenal Ulcers

Introduction to Sucralfate

• The American College of Cardiology notes that sucralfate forms an ulcer-adherent complex at duodenal ulcer sites, protecting the ulcer and promoting healing 1
• The American College of Cardiology states that sucralfate is effective for NSAID-associated duodenal ulcers, particularly when the NSAID is discontinued 1
• The American College of Cardiology indicates that sucralfate is not effective for treatment or prevention of NSAID-related gastric ulcers 1
• The American College of Cardiology recommends that sucralfate is not used for gastric ulcer prevention due to the availability of superior alternatives such as PPIs 1
• The American College of Cardiology suggests that PPIs are the preferred agents for therapy and prophylaxis of NSAID and ASA-associated GI injury 1

Dosage and Administration

• No cited facts are available for this section.

Efficacy and Safety

• No unique cited facts are available for this section, beyond those already mentioned.