Complications in Spinal Muscular Atrophy

Nutritional and Gastrointestinal Complications

• SMA patients frequently experience malnutrition, with studies showing up to 65% of patients being malnourished 1, 2
• Nutritional deficiencies, particularly calcium absorption issues, have been documented in up to 84% of patients in some populations 1, 2
• Gut microbiota alterations have been observed in SMA patients compared to healthy controls, which may play a role in disease progression 1, 2