Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/26/2025

Aconite Poisoning Management

Immediate Supportive Care

  • The American Heart Association recommends stabilization of vital functions before the specific toxin is identified, with timely supportive care taking precedence over antidotal therapy, including airway management and hemodynamic support with correction of critical vital sign abnormalities 1, 2
  • The American Heart Association suggests 100% oxygen administration to maintain tissue oxygenation 1
  • Contacting regional poison control centers, such as the US center at 1-800-222-1222, is recommended for expert guidance, as board-certified toxicologists can provide specialized treatment recommendations 1, 2

Extracorporeal Toxin Removal

  • The Society of Critical Care Medicine indicates that the role of charcoal hemoperfusion to remove circulating aconitine alkaloids is not established, unlike other poisonings where extracorporeal treatment has clear indications 3, 4, 5