Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/22/2025

Vyvanse Dosage Guidelines for ADHD

Introduction to Vyvanse Dosage

  • Alternative guideline recommendations suggest starting Vyvanse at 20-30 mg daily for patients with ADHD, according to the American College of Obstetricians and Gynecologists 1, 2

Titration and Monitoring

  • Systematically assess for specific stimulant side effects, including insomnia, anorexia, headaches, and weight loss at each dose adjustment, as recommended by clinical guidelines 3
  • Collect standardized ADHD rating scales from patients and significant others before each dose increase, to objectively track response 3
  • Maintain weekly contact during initial titration to assess response and side effects, as suggested by clinical guidelines 3

Special Considerations

  • If adequate symptom control is not achieved at 70 mg daily, consider alternative treatments or adding non-stimulant medications rather than exceeding the maximum dose, as recommended by clinical guidelines 3
  • Document clearly that symptoms could not be controlled at lower doses before considering any alternative approaches, to ensure optimal treatment outcomes 3

REFERENCES

3

Dosing and Monitoring of Vyvanse for ADHD [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025