Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/4/2025

Diarrhea Incidence with Nitrofurantoin

Gastrointestinal Side Effects

  • The most common adverse effects with nitrofurantoin are nausea and headache rather than diarrhea, according to Praxis Medical Insights 1

Comparative Incidence

  • Diarrhea incidence with nitrofurantoin is significantly lower than with many chemotherapeutic agents, which can cause diarrhea in 30-50% of patients, as reported by Annals of Oncology 2, 3

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