Treatment of Histrionic Personality Disorder with Comorbid Conditions

Pharmacotherapy for Comorbid Conditions

• For patients with histrionic personality disorder and comorbid depression, the American College of Physicians recommends considering SSRIs or cognitive-behavioral therapy per established depression treatment protocols, with a moderate strength of evidence 1, 2
• For patients with histrionic personality disorder and comorbid anxiety disorders, the International College of Neuropsychopharmacology suggests that SSRIs or SNRIs may be appropriate based on the specific anxiety disorder present, with a moderate strength of evidence 3, 4