Injectable Paracetamol Dosing in Children

Preparation and Administration

• Paracetamol for IV use can be diluted in 0.9% normal saline (NS) or 5% dextrose (D5W) if needed for smaller volumes in neonates, according to the American Academy of Pediatrics 1, 2
• The standard concentration of paracetamol in commercial preparations is 10 mg/mL 2
• For a 10 mg/mL solution, a 7.5 mg/kg dose for a 5 kg infant equals 37.5 mg, which is equivalent to 3.75 mL of solution, as recommended by the Pediatrics journal 1