Optimizing Sumatriptan Dosage for Migraine Treatment

Dose Adjustment and Efficacy

• Patients should try a medication for 2-3 headache episodes before abandoning that line of therapy 1

Managing Treatment Failure

• If the patient continues to have inadequate response after dose optimization, consider combining sumatriptan with an NSAID or acetaminophen 3
• Switching to another triptan (almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, or zolmitriptan) may be beneficial 2, 3

Side Effect Management

• Common side effects of sumatriptan include nausea, warmth, vomiting, vertigo, malaise, headache, chest pressure and heaviness 2
• If the patient experiences unpleasant sensory disturbances with sumatriptan, trying a different triptan may be beneficial 1