Pediatric Cancer Epidemiology and Treatment

Central Nervous System Tumors

CNS tumors are the leading cause of cancer-related death in children, with medulloblastomas being the predominant embryonal tumors, according to the National Comprehensive Cancer Network 1
The incidence rate of primary CNS tumors in children <20 years was 6.23 per 100,000 population between 2014 and 2018, as reported by the Central Brain Tumor Registry of the United States 1
A multidisciplinary approach involving pediatric oncologists, radiation oncologists, pathologists, neuroradiologists, and neurosurgeons is strongly encouraged for optimal outcomes in treating CNS tumors 1

Almost 80% of children with Wilms' tumor can be treated successfully with modern diagnostic and therapeutic approaches, as stated by the American Academy of Pediatrics 3
Cancer is the second leading cause of death in children older than 3 months, highlighting the need for continued advances in treatment, according to the American Academy of Pediatrics 3

Neuroblastoma is the most common extracranial solid tumor and the most common intra-abdominal solid tumor in children, although this fact is from Praxis Medical Insights, it is still a relevant guideline summary point 2