Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/19/2025

Gaze Deviation in Occipital Stroke

Clinical Presentation and Diagnosis

  • Skew deviation, a vertical strabismus associated with posterior fossa lesions including stroke, can be a critical sign requiring urgent recognition in patients with gaze deviation following stroke, presenting with diplopia and blurred vision 1, 2
  • The examination should include complete ophthalmic assessment with emphasis on sensorimotor evaluation, looking for other neuro-ophthalmic signs such as Horner's syndrome, cranial nerve palsy, or nystagmus in patients with gaze abnormalities following stroke 2
  • Distinguishing between different causes of gaze abnormalities is crucial as they may indicate serious brainstem pathology requiring immediate intervention, according to Praxis Medical Insights 3

Diagnostic Imaging

  • MRI of the brain is typically preferred over CT for evaluating post-chiasmal visual symptoms, particularly in subacute, slowly progressive presentations, as recommended by the American College of Radiology 4
  • In acute settings with sudden onset of visual symptoms or diplopia, urgent imaging of the brain and brainstem (MRI with and without contrast) should be performed to evaluate for stroke, demyelination, or mass lesions in patients with gaze deviation following stroke 1
  • Patients presenting with acute onset of diplopia may have deficits related to a posterior circulation stroke, requiring appropriate neuroimaging, as suggested by the American College of Radiology 4

Management Considerations

  • Treatment approaches should be directed at the underlying cause of the gaze deviation in patients with gaze abnormalities following stroke 2
  • Patients with gaze abnormalities following stroke should be monitored and may benefit from referral to specialists in neuro-ophthalmology, as recommended by the American Academy of Ophthalmology 2

Important Caveats

  • The presence of additional neurological symptoms alongside gaze deviation warrants immediate neurological evaluation in patients with gaze deviation following stroke 1
  • Distinguishing between skew deviation and fourth nerve palsy is critical, as skew deviation may indicate serious brainstem pathology requiring urgent intervention in patients with gaze deviation following stroke 1