Management of Polydipsia Without Hyperglycemia

Diagnostic Approach

• The American Diabetes Association recommends checking fasting glucose and HbA1c to definitively exclude diabetes mellitus as the cause of polydipsia, even in the absence of hyperglycemia 1, 2

Management Based on Diagnosis

• The Endocrine Society suggests that desmopressin acetate is the definitive treatment for Central Diabetes Insipidus (CDI), with strict monitoring of serum sodium levels to avoid hyponatremia 1, 2