Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/12/2025

Elastography Results Interpretation

Liver Stiffness Measurement

  • A liver stiffness measurement of 4.8 kPA indicates normal liver elasticity with no evidence of significant fibrosis or cirrhosis, with a cutoff of 7.1-7.9 kPA suggesting mild to moderate fibrosis in non-alcoholic fatty liver disease (NAFLD), as per the American Association for the Study of Liver Diseases 1
  • This measurement is significantly lower than the 12.5 kPA threshold used to diagnose cirrhosis in patients with chronic liver diseases, according to the American Gastroenterological Association 2, 3
  • The value falls within the normal range of liver stiffness, with the upper limit of normal being approximately 5-5.5 kPA, as stated by the American Association for the Study of Liver Diseases 4

Controlled Attenuation Parameter and Vibration-Controlled Transient Elastography Fat Fraction

  • The attenuation coefficient (ACE) of 270 dB/m indicates moderate hepatic steatosis, and the VDFF of 10.8% represents a moderate degree of hepatic steatosis, consistent with the ACE measurement, as per the American Association for the Study of Liver Diseases 4
  • The presence of steatosis is confirmed by the ACE and VDFF measurements, but the normal liver stiffness value suggests that there is no significant fibrosis at this time, according to the American Association for the Study of Liver Diseases 5, 6

Clinical Implications and Recommendations

  • These findings are consistent with non-alcoholic fatty liver disease (NAFLD) without significant fibrosis, with a low risk of liver-related complications, as stated by the American Gastroenterological Association 6, 1
  • Regular monitoring is recommended, as NAFLD can progress over time, particularly with metabolic risk factors, according to the American Association for the Study of Liver Diseases 6
  • No need for liver biopsy at this stage, as non-invasive tests are sufficient for monitoring, as per the American Gastroenterological Association 3