Aripiprazole Dosage Considerations for Adults with Schizophrenia

Special Populations and Dosage Adjustments

• Lower starting doses of aripiprazole should be considered in older patients and patients with hepatic impairment, as recommended by the American Geriatrics Society and the National Institute for Health and Care Excellence 1, 2

Pharmacokinetics

• The mean elimination half-life of aripiprazole is approximately 75 hours, although this fact is not directly associated with a specific guideline society, it is a relevant pharmacokinetic property 1, 2