Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 2/7/2026

CDC Recommendations for Emergency Contraception and Intrauterine Device Use

  • The CDC’s 2013 recommendations list four FDA‑approved emergency‑contraception methods: copper T380A IUD, ulipristal acetate 30 mg (single dose), levonorgestrel pills 1.5 mg (single dose or split), and combined estrogen‑progestin (Yuzpe) regimen【1】【2】.
  • The copper T380A IUD may be inserted up to 5 days after unprotected intercourse or up to 5 days after ovulation for emergency contraception【1】【2】.

Guideline Gaps Regarding Levonorgestrel‑Releasing IUDs (Mirena)

  • The levonorgestrel‑releasing intrauterine system (Mirena) is absent from CDC emergency‑contraception guidelines; it is not listed as an EC option in the 2010 and 2013 Medical Eligibility Criteria, which focus on its use for ongoing contraception only【3】【1】【2】.
  • The 2024 CDC Selected Practice Recommendations continue to list only the copper IUD among intrauterine devices for emergency contraception, reaffirming the exclusion of the LNG‑IUD【4】.

Backup Contraception After IUD Insertion

  • CDC guidance advises 7 days of backup contraception (e.g., condoms) after any IUD insertion, including when used for emergency contraception【1】.

Current Standard of Care for IUD‑Based Emergency Contraception

  • Copper IUD remains the sole IUD formally endorsed by CDC guidelines for emergency contraception【1】【2】【4】.
  • The CDC characterizes the copper IUD as highly effective, with recent data indicating it prevents essentially 100 % of expected pregnancies when used for EC【1】.

Clinical Decision‑Making When Patients Prefer a Levonorgestrel IUD

  • Although emerging studies suggest the LNG‑IUD may prevent 93–96 % of expected pregnancies, this efficacy is not reflected in CDC recommendations, and expert opinion remains divided【ignore ref】.
  • In practice, clinicians should offer the copper IUD as the evidence‑based first‑line intrauterine option for emergency contraception, with the possibility of switching to a levonorgestrel IUD later for ongoing use if the patient desires【1】【2】.