Medication Safety During Lactation for Gastritis

Anti-inflammatory Medications

Low-dose corticosteroids (prednisone <20 mg daily) are compatible with breastfeeding, according to the American Academy of Pediatrics, but for doses ≥20 mg daily, it's recommended to delay breastfeeding or discard breast milk accumulated in the 4 hours following administration 1, 2
NSAIDs are conditionally recommended as compatible with breastfeeding for short-term use, with a strength of evidence based on limited human data 1, 2

Amoxicillin/clavulanic acid is safe during breastfeeding based on limited human data, with a low risk of adverse effects in infants 3, 4
Macrolides (clarithromycin, azithromycin) are generally considered safe, but there is a very low risk of infantile hypertrophic pyloric stenosis in infants exposed during the first 13 days of breastfeeding, as reported by the European Respiratory Journal 4, 5 is replaced with:
Macrolides (clarithromycin, azithromycin) are generally considered safe, but there is a very low risk of infantile hypertrophic pyloric stenosis in infants exposed during the first 13 days of breastfeeding 4
Metronidazole is deemed safe based on cohort studies showing no significant adverse effects in infants, with a strength of evidence based on human data 3

Methotrexate should be avoided during breastfeeding as it may accumulate in neonatal tissues despite minimal passage into breast milk, according to Gastroenterology and Arthritis care & research 1, 2, 6
Cyclophosphamide is strongly recommended against during breastfeeding, with a high strength of evidence based on human data 1, 2