Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/4/2025

Safety of Cromolyn Sodium Eye Drops in Diabetes

Mechanism of Action and Safety Profile

  • Cromolyn sodium works by inhibiting the degranulation of sensitized mast cells, thereby preventing the release of mediators of the allergic response and inflammation, according to the American Academy of Allergy, Asthma, and Immunology 1
  • The medication has an excellent safety profile with minimal systemic absorption, making it suitable for patients with various comorbidities, as stated by the American Gastroenterological Association and the American Academy of Allergy, Asthma, and Immunology 1, 2

Advantages for Diabetic Patients

  • The medication's local action in the eye minimizes risk of drug interactions with diabetes medications, as noted by the American Academy of Allergy, Asthma, and Immunology 1