Sebopsoriasis Diagnosis and Treatment

Etiology and Pathophysiology

The American Academy of Dermatology suggests that sebopsoriasis has a multifactorial etiology, with genetic predisposing factors similar to those of psoriasis, a chronic, systemic, and genetic inflammatory disorder 1
Environmental factors such as stress, systemic infections, and medications can trigger exacerbations, as noted by the American Academy of Dermatology 2
The pathophysiology of sebopsoriasis involves an immunologically mediated inflammatory process with inappropriate activation of cutaneous T cells and dendritic cells, leading to the release of cytokines and soluble mediators that cause hyperproliferation of keratinocytes, as described by the American Academy of Dermatology 3

The American Academy of Dermatology recommends considering psoriasis vulgar as a differential diagnosis for sebopsoriasis 1
Dermatitis atópica, dermatitis de contacto, linfoma cutáneo de células T, and pitiriasis rubra pilaris should also be considered as differential diagnoses, according to the American Academy of Dermatology 2

The American Academy of Dermatology suggests an stepped approach to treatment based on symptom severity, with corticosteroids, gentle cleansers, and moisturizers as first-line treatments 4
The use of antihistamines, corticosteroids, and other medications may be necessary for second-line treatment, as recommended by the American Academy of Dermatology 4