Frequency of Primary Tumors Causing Hepatic Metastases

Most Common Sources

• The gastrointestinal tract—especially colorectal cancer—is the leading origin of liver metastases, with the pancreas, breast, and lung following in frequency. 1
• Colorectal cancer accounts for the highest proportion of hepatic metastases, with about 80 % of its metastatic spread occurring in the liver. 1

Secondary Sources

• Pancreatic cancer is identified as a frequent contributor to liver metastases after gastrointestinal tumors. 1
• Breast cancer commonly metastasizes to the liver. 1
• Lung cancer frequently spreads to the liver. 1

Less Common Sources

• Renal cell carcinoma can give rise to liver metastases. 1
• Melanoma, including ocular melanoma, is capable of hepatic metastasis. 1
• Sarcoma, including gastrointestinal sarcoma, may metastasize to the liver. 1