Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/15/2025

Amoxicillin Dosage Guidelines for Pediatric Patients

Introduction to Dosage Recommendations

  • The maximum daily dose of amoxicillin for pediatric patients is 90 mg/kg/day with a maximum of 4000 mg/day (4 g/day), as recommended by the American Academy of Pediatrics, based on evidence from Clinical Infectious Diseases 1

Dosing Considerations for Community-Acquired Pneumonia

  • For community-acquired pneumonia in children, the recommended dose is 90 mg/kg/day in 2 doses with a maximum of 4000 mg/day, according to the Infectious Diseases Society of America 1

Maximum Daily Dose for Pediatric Patients

  • The maximum daily dose for children weighing 40 kg or more is 4000 mg/day (e.g., one 2000-mg tablet twice daily), as stated by the American Academy of Pediatrics, with evidence from Clinical Infectious Diseases 1