Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/30/2025

Safety of Simethicone During Pregnancy

Clinical Evidence and Guidelines

  • Gastrointestinal symptoms are common during pregnancy, and safe symptom management is important for maternal quality of life 1
  • When considering any medication during pregnancy, the benefit of symptom relief should be weighed against potential risks 2, 3

Practical Recommendations

  • If gastrointestinal symptoms are severe or persistent during pregnancy, evaluation for underlying conditions may be warranted before attributing symptoms solely to normal pregnancy changes 1
  • As with all medications in pregnancy, use the lowest effective dose for the shortest duration needed to manage symptoms 2, 3