Globus Sensation Characteristics and Management

Introduction to Globus Sensation

• Globus sensation typically improves during eating rather than worsening when swallowing food, which is a key feature in distinguishing it from dysphagia 1, 2
• The sensation presents as a recurrent, non-painful but uncomfortable feeling of a lump in the throat, more obvious between meals and typically improving with eating 1, 2, 3

Distinguishing Globus Sensation from Dysphagia

• Globus must be distinguished from dysphagia, a separate condition characterized by difficulty swallowing, although they can co-occur in some patients 1, 2
• Approximately 20% of patients with functional dysphagia may experience globus sensation with swallowing, but true globus typically improves rather than worsens with food intake 1, 2

Associated Conditions and Management

• Globus sensation is often linked to psychological stress, with many patients reporting symptom exacerbation during periods of high emotional intensity 1, 2
• It commonly co-occurs with functional voice disorders and is frequently associated with throat clearing, sense of mucus buildup, dry throat, and repeated swallowing 1, 2
• Mistaking globus for dysphagia can lead to inappropriate treatment approaches 1, 2