Clinical Applications of Atrovent and DuoNeb

Indications and Usage

• The American Academy of Allergy, Asthma, and Immunology recommends Atrovent for rhinorrhea associated with allergic/nonallergic rhinitis (nasal spray formulation 0.03%) 1
• The American Academy of Family Physicians suggests using Atrovent for common cold-associated rhinorrhea (nasal spray 0.06%) 1
• The American College of Chest Physicians recommends Atrovent for patients requiring only anticholinergic bronchodilation 2, 3
• The American Academy of Family Physicians recommends DuoNeb for COPD exacerbations requiring maximal bronchodilation 4

Safety and Efficacy

• The Journal of Allergy and Clinical Immunology reports that both Atrovent and DuoNeb do not alter physiologic functions like mucociliary clearance or ciliary beat frequency 5, 1
• The Journal of Allergy and Clinical Immunology notes that common adverse effects of Atrovent and DuoNeb include epistaxis (9%) and nasal dryness (5%) for nasal formulations 6, 1