Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/7/2025

Exertional Heat Stroke Management

Introduction to Cooling Methods

  • The American College of Critical Care Medicine recommends immediate aggressive cooling for exertional heat stroke, with cold-water immersion being the gold standard if available, or alternatively applying ice packs to the neck, axilla, and groin while using evaporative cooling methods 1, 2

Optimal Cooling Protocol

  • Whole-body cold-water immersion at 14-15°C is the gold standard for exertional heat stroke in young, fit patients, with a target cooling rate of ≥0.155°C/min 1, 2
  • The cooling method should continue for 15 minutes or until neurological symptoms resolve, whichever occurs first 2
  • If cold-water immersion is not available, alternative methods include applying ice packs to the neck, axilla, and groin, and using evaporative cooling with wet skin and continuous fanning 2, 5, 6

Critical Concurrent Management

  • The patient's hypotension requires immediate attention alongside cooling, with a mortality rate of 33% compared to 10% in normotensive patients 6
  • Establish IV access and begin fluid resuscitation, titrating fluids to restore blood pressure and tissue perfusion 2, 7, 8
  • Consider invasive hemodynamic monitoring if hypotension persists after initial cooling and fluids 7

Seizure and Airway Management

  • The patient should be monitored for recurrent seizures during cooling, and airway patency should be maintained given his altered mental status 2, 9
  • Consider intubation if the patient cannot protect his airway during aggressive cooling 9

Common Pitfalls to Avoid

  • Antipyretics and dantrolene should not be used in heat stroke management, as they are ineffective and may worsen coagulopathy and liver injury 5, 6
  • Cooling should not be delayed for diagnostic workup, and should continue until core temperature reaches 39°C or neurological symptoms resolve 3, 5, 2

Monitoring Requirements

  • Continuous core temperature monitoring and frequent neurological assessments are necessary to detect improvement or deterioration 2, 9
  • Monitor for multi-organ dysfunction, including rhabdomyolysis, acute kidney injury, liver injury, coagulopathy, and cardiac dysfunction 1, 2