Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/2/2025

Kidney Stone Prevention Guidelines

Primary Dietary Recommendations

  • The American Urological Association recommends achieving at least 2.5 liters of urine output daily regardless of beverage choice, as this is supported by randomized controlled trial evidence 1
  • The American Urological Association suggests maintaining normal dietary calcium intake of 1,000-1,200 mg/day rather than restricting it, as higher dietary calcium actually reduces stone risk 1
  • The American Urological Association advises limiting sodium intake to 100 mEq (2,300 mg) daily, as this reduces urinary calcium excretion 1

Beverage Selection Context

  • Observational studies show that coffee, tea (caffeinated and decaffeinated), beer, and wine are associated with reduced stone risk 1, 2
  • Orange juice showed no association with stone risk in observational studies, while grapefruit juice increased stone formation risk by 40% and should be avoided 2, 3

Pharmacologic Therapy

  • For patients with documented hypocitraturia or recurrent stones despite dietary measures, potassium citrate remains the first-line pharmacological therapy, according to the American Urological Association 1

REFERENCES

3

Caffeine and Kidney Stone Disease Management [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025