Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/26/2025

Open Gastrojejunostomy Procedure

Preoperative Preparation

  • The American Society for Gastrointestinal Endoscopy recommends that patients should be kept nil per os (NPO) past midnight for a procedure the following day, though clear liquids may be provided up to 2 hours before the procedure to reduce aspiration risk 3
  • Antibiotic prophylaxis with a first-generation cephalosporin or similar agent that covers typical cutaneous organisms should be administered, especially for patients at high risk of infection 3
  • Coagulation parameters should be optimized before the procedure, with INR less than 1.5 and platelet count greater than 50,000/L 3

Surgical Approach and Technique

  • The stomach should be mobilized to ensure proper exposure of the anterior gastric wall 4
  • The gastrostomy should be positioned to the right of midline and lower in the antrum to allow for a shorter, more direct route for the jejunal tube through the pylorus 1, 5
  • This positioning will minimize gastric looping and help prevent proximal migration of the jejunal component 5
  • An incision should be made in the anterior wall of the stomach 4

Tube Placement

  • The gastrostomy tube should be inserted through the abdominal wall into the stomach 1, 4
  • The jejunal extension tube should be advanced through the gastrostomy tube, through the pylorus, and into the jejunum beyond the ligament of Treitz 1, 5
  • Fluoroscopic guidance should be used to confirm proper positioning of the jejunal extension tube 1, 6
  • The tube should be secured in place and patency confirmed by injecting contrast material 5

Post-Procedure Management

  • Continuous rather than bolus feeding through the jejunal port is required due to loss of the stomach reservoir 7
  • Mechanical issues, such as tube kinking or coiling in the stomach, should be monitored 7

Special Considerations

  • In patients with ascites, malnourishment, or steroid treatment, gastropexy sutures are imperative to prevent leakage 4
  • For patients with upper GI stenosis, image-guided jejunostomy is favored as it prevents the need for endoscope passage 5
  • Success rates for percutaneous gastrojejunostomy range from 90% to 100%, with similar outcomes between endoscopy-guided and fluoroscopy-guided techniques 5

Common Pitfalls and How to Avoid Them

  • Tube dislocation or migration can be avoided by cutting the external gastrostomy tube length to shorter than 10 cm and using an extension tube of longer length 1, 6
  • Gastric looping can be prevented by positioning the gastrostomy to the right of midline and lower in the antrum 1, 5
  • Difficult jejunal access can be overcome by using a stiff wire or sometimes two wires 1, 5
  • Infection risk can be prevented by proper antibiotic prophylaxis and aseptic technique 3

REFERENCES

6

Gastrojejunostomy Tube Placement and Management [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025