Clindamycin Use in Staphylococcal Scalded Skin Syndrome (SSSS)

Pediatric Considerations

• The Infectious Diseases Society of America recommends clindamycin dosing for hospitalized children with complicated skin infections, such as SSSS, at 10-13 mg/kg/dose IV every 6-8 hours, only if local clindamycin resistance rates are low (<10%) 1
• This pediatric dosing guideline applies when clindamycin is used as adjunctive therapy in SSSS, highlighting the importance of considering resistance rates in treatment decisions 1