Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/30/2025

Electrodesiccation and Curettage for Basal Cell Carcinoma

Understanding ED&C Technique

  • The National Comprehensive Cancer Network recommends that ED&C involves alternating cycles of curettage and electrodesiccation, typically performed up to 3 cycles per session, with the endpoint determined by the operator's ability to feel firm, normal dermis versus soft tumor tissue with the curette 1
  • The American Academy of Dermatology notes that no histologic margin assessment is possible with ED&C, making it unsuitable for tumors requiring margin verification 1

Appropriate Patient Selection for ED&C

  • The American Academy of Dermatology suggests that ED&C should only be considered for properly selected low-risk tumors in non-terminal hair-bearing locations, with low-risk primary BCC (well-defined, <2 cm, non-aggressive histology) being an acceptable indication 2, 4
  • The National Comprehensive Cancer Network recommends that trunk and extremity locations are preferred, and superficial lesions only should be treated with ED&C 1

Critical Contraindications

  • The National Comprehensive Cancer Network and the American Academy of Dermatology agree that terminal hair-bearing areas (scalp, beard, pubic, axillary regions) are absolutely contraindicated due to risk of follicular tumor extension that the curette cannot detect 1, 5
  • The National Comprehensive Cancer Network notes that if subcutaneous fat is reached during curettage, the procedure should be abandoned and surgical excision performed instead—the curette cannot distinguish tumor from soft adipose tissue 1, 6

Reported Outcomes

  • The National Comprehensive Cancer Network reports that five-year cure rates for appropriately selected cases range from 91-97%, but some studies report recurrence rates of 19-27% when used for high-risk locations or aggressive subtypes 1
  • The National Comprehensive Cancer Network notes that results are highly operator-dependent and optimal outcomes require experienced practitioners 1

Comparison to Surgical Excision

  • The National Comprehensive Cancer Network recommends that low-risk primary BCC requires 4-mm clinical margins for >95% complete removal when surgical excision is chosen instead 7, 8, 3, 4
  • The National Comprehensive Cancer Network suggests that high-risk BCC requires Mohs micrographic surgery or wider margins with complete margin assessment 7, 8

REFERENCES

1

basal cell skin cancer, version 1.2016, nccn clinical practice guidelines in oncology. [LINK]

Journal of the National Comprehensive Cancer Network : JNCCN, 2016

2

guidelines of care for the management of basal cell carcinoma. [LINK]

Journal of the American Academy of Dermatology, 2018

3

guidelines of care for the management of basal cell carcinoma. [LINK]

Journal of the American Academy of Dermatology, 2018

4

guidelines of care for the management of basal cell carcinoma. [LINK]

Journal of the American Academy of Dermatology, 2018

5

basal cell skin cancer, version 1.2016, nccn clinical practice guidelines in oncology. [LINK]

Journal of the National Comprehensive Cancer Network : JNCCN, 2016

6

basal cell skin cancer, version 1.2016, nccn clinical practice guidelines in oncology. [LINK]

Journal of the National Comprehensive Cancer Network : JNCCN, 2016

7

basal cell skin cancer, version 1.2016, nccn clinical practice guidelines in oncology. [LINK]

Journal of the National Comprehensive Cancer Network : JNCCN, 2016

8

guidelines of care for the management of basal cell carcinoma. [LINK]

Journal of the American Academy of Dermatology, 2018