Dexamethasone Dosing for Croup in Children

Clinical Considerations for Dexamethasone Administration

• For severe cases, dexamethasone may be used in conjunction with nebulized epinephrine (0.5 mL/kg of 1:1000 solution, maximum 5 mL) for more rapid symptom relief 1

Safety Considerations

• High-dose dexamethasone (0.5mg/kg/day) has been associated with adverse neurodevelopmental outcomes in preterm infants when used for extended periods, though this is less relevant for the single-dose regimen typically used in croup 2