Hypocalcemia in Acute Pancreatitis

Primary Mechanisms and Contributing Factors

• Hypocalcemia occurs in up to 25% of patients with severe acute pancreatitis, according to Clinical Nutrition guidelines 1
• The systemic inflammatory response and release of proinflammatory cytokines contribute to metabolic derangements, as noted by Clinical Nutrition 1
• Associated deficiencies of magnesium, zinc, folate, and thiamine may develop during hospitalization, as reported by Clinical Nutrition 1
• Adequate fluid resuscitation and hemodynamic stabilization are essential before addressing electrolyte abnormalities, as recommended by Clinical Nutrition 1