Safety of Montair LC During Pregnancy

Introduction to Montair LC Safety

The American College of Rhinology recommends avoiding Montair LC during pregnancy for chronic rhinosinusitis management, though montelukast alone may be considered for recalcitrant asthma if the patient has shown a favorable response prior to pregnancy 1
Antihistamines, such as levocetirizine, should be used with caution during pregnancy, with second-generation antihistamines preferred over first-generation ones due to their better safety profile 2
First-generation antihistamines should be avoided during pregnancy given their sedative and anticholinergic properties 3

For allergic rhinitis management during pregnancy, second-generation antihistamines are generally preferred over first-generation ones due to their better safety profile 4
Intranasal corticosteroids may be used during pregnancy because of their safety and efficacy profile 4
When considering medication use during pregnancy, the clinician should compare the benefits and risks of each medication, balancing maternal risk of therapy versus no therapy and the fetal risk of uncontrolled maternal disease with the risk of therapy on the newborn 5

For rhinosinusitis management during pregnancy, saline nasal rinses and topical corticosteroid nasal sprays are the preferred first-line options 1
Oral decongestants should not be used during pregnancy 3
Avoid anti-leukotrienes for CRS maintenance during pregnancy, but montelukast alone may be considered for recalcitrant asthma if the patient has shown a favorable response prior to pregnancy 1
Inhaled medications have been used for many years without documentation of adverse effects on the fetus, and untreated asthma resulting in severe exacerbation with maternal hypoxia has well-described adverse effects on the fetus 6