Augmentin Dosage for Pneumonia in Adults

Dosage Recommendations

For healthy outpatients without comorbidities, the American Thoracic Society recommends amoxicillin 1 g three times daily as the preferred first-line therapy, with doxycycline 100 mg twice daily or macrolides as alternatives 1, 2
For outpatients with comorbidities, the American Thoracic Society recommends Augmentin as part of combination therapy, with dosage options including 500 mg/125 mg three times daily or 875 mg/125 mg twice daily, and should be combined with a macrolide or doxycycline 1, 2

The American Thoracic Society advises against using macrolide monotherapy in areas with high pneumococcal resistance to macrolides (≥25%) 1, 2
The Infectious Diseases Society of America recommends considering alternative antibiotics for patients not improving on initial therapy 4

For patients with recent exposure to antibiotics within the previous 3 months, the Infectious Diseases Society of America suggests selecting an alternative from a different class 4