Association of Peanut Allergy with Other Allergies and Atopic Conditions

Co-Existing Food Allergies

Peanut-allergic patients show 59-86% sensitization to tree nuts, with 33-34% demonstrating clinical reactivity 1, 2
Higher specific IgE correlations exist between peanut and certain tree nuts, particularly almond and hazelnut 1, 2
Peanut-allergic patients demonstrate 19-79% sensitization to soy and other legumes, but only 3-5% show clinical reactivity 1, 2
When lupine challenges were performed in peanut-sensitized patients, 28-30% reacted clinically 1, 2
Sensitization to lentils and chickpeas may indicate increased risk for multiple legume allergies 1, 2
30.4% of children with reported food allergy have multiple food allergies 3

Severe eczema within the first 6 months of life is strongly associated with increased risk of developing peanut, milk, and egg allergy 4, 3
Food allergy and atopic dermatitis are highly associated conditions 5
Asthma and food allergy frequently coexist in both pediatric and adult patients 5
Children with food allergy have 4 times higher odds of having asthma 3
Conversely, 44% of children diagnosed with asthma have an existing food allergy 3
Food allergy is associated with severe asthma and may be a risk factor for severe asthma exacerbations 5
Asthma is a critical moderating factor for severe allergic reactions and is associated with increased risk of fatal anaphylaxis from peanut 3
The "allergic march" describes progression from atopic dermatitis in the first year of life to allergic rhinitis, asthma, and food allergy 4, 3
Patients with one atopic condition are predisposed to developing multiple allergic conditions 4, 3