Tadalafil Dosage and Efficacy for Erectile Dysfunction

Efficacy and Dosage

• The American Urological Association suggests that tadalafil's efficacy is not dose-dependent between 5-20 mg, making lower daily doses an effective option for erectile dysfunction treatment 1, 2

Advantages of Daily Dosing

• Daily tadalafil dosing may be particularly beneficial for couples who prefer spontaneous rather than scheduled sexual activity, as it eliminates the need to time medication with sexual activity 3

Special Considerations

• The European Association of Urology recommends that for men with renal impairment and creatinine clearance 30-50 mL/min, tadalafil should be started with 2.5 mg and may be increased to 5 mg based on response, according to The Journal of Urology 4
• Men with diabetes or post-prostatectomy may have more severe erectile dysfunction at baseline and may respond less robustly to phosphodiesterase type 5 inhibitors, as reported in The Journal of Urology 4