Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/22/2025

Severe Traumatic Brain Injury Management

Primary Diagnosis

  • The patient has sustained severe traumatic brain injury (TBI) with multiple hemorrhagic lesions, requiring immediate neurosurgical consultation, close neurological monitoring, and aggressive management to prevent secondary brain injury and death 1, 2
  • Hemorrhagic contusions are present in bilateral frontal and temporal lobes 1
  • Minimal subacute subdural hemorrhage is present in right frontoparietal and left temporoparietal regions 1
  • Linear frontal bone fracture extends to vertex with subgaleal hematoma 3
  • Atherosclerotic disease is present in vertebrobasilar and bilateral internal carotid arteries 3

Critical Management Priorities

Immediate Hemodynamic Management

  • Maintain systolic blood pressure >110 mmHg at all times to prevent secondary brain injury and reduce mortality 2, 4
  • Use vasopressors (phenylephrine or norepinephrine) immediately if hypotension develops rather than waiting for fluid resuscitation effects 2

Neurosurgical Consultation

  • Immediate neurosurgical evaluation is mandatory given the presence of acute subdural hemorrhage, multiple hemorrhagic contusions, and skull fracture 5
  • Neurosurgical intervention may be required if subdural thickness exceeds 5 mm with midline shift >5 mm, or if there is clinical deterioration 5

CT Angiography Indication

  • CT angiography of supra-aortic and intracranial vessels should be performed urgently given multiple risk factors, including basal skull fracture, advanced atherosclerotic disease, and focal neurological findings 3, 4

Secondary Diagnoses Requiring Attention

Respiratory Compromise

  • Airway control and ventilation monitoring are critical priorities 2, 3
  • Close monitoring of respiratory status is essential as hypoxia will worsen brain injury 2

Cardiac Concerns

  • Tachycardia (HR 117) with regular rhythm is present 1
  • Periorbital edema (bilateral) is likely related to facial trauma and retro-orbital ecchymosis rather than cardiac or endocrine causes, but requires further evaluation 1

Critical Information That Must Be Elicited

Anticoagulation/Antiplatelet Status

  • It is critical to determine immediately if the patient is taking any anticoagulant or antiplatelet agents, as this information is vital for management 6

Detailed Fall Mechanism

  • Exact height of fall, surface landed on, witnessed loss of consciousness, seizure activity, and alcohol intoxication at time of fall should be documented 7

Neurological Baseline Assessment

  • Exact GCS components, pupillary size and reactivity, motor strength in all extremities, cranial nerve examination, and any focal deficits should be documented 1, 8

Comorbidity Verification

  • Verification of comorbidities, including hypertension, diabetes, prior stroke or TIA, atrial fibrillation, and chronic kidney disease, is necessary 6, 9

Functional Status Details

  • Baseline ambulation, cognitive function, history of prior falls, and vision or hearing impairment should be assessed 10

Medication Reconciliation

  • Verification of medication use, including recent changes, compliance, and borrowed medications, is necessary 1, 6

Monitoring Requirements

  • The patient requires neurosurgical intensive care unit admission, continuous neurological assessment, repeat CT head within 6-12 hours, continuous cardiac monitoring, strict blood pressure management, and consideration of intracranial pressure monitoring if neurological deterioration occurs 1, 2, 5