Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/16/2025

Tapering Lunesta (Eszopiclone) 3mg

  • Consider reducing the dose by approximately 25% every 1-2 weeks, for example, reducing Lunesta 3mg to 2mg for 1-2 weeks, then to 1mg for 1-2 weeks, and finally discontinuing completely, as recommended by Praxis Medical Insights 1

Managing Withdrawal Symptoms

  • Non-pharmacological approaches like sleep hygiene practices, cognitive behavioral therapy for insomnia, and relaxation techniques can be beneficial for managing temporary symptoms during tapering, as suggested by Praxis Medical Insights 1
  • Over-the-counter sleep aids may help manage temporary symptoms during tapering, according to Gastroenterology 2

Special Considerations

  • If you're also taking other CNS depressants, consult your healthcare provider about which medication to taper first, as advised by Praxis Medical Insights 1
  • Patients with a history of seizures or other medical comorbidities may require specialist supervision during tapering, as recommended by Praxis Medical Insights 1

REFERENCES

1

Benzodiazepine Discontinuation [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025