Skin Abscess Healing Time
Expected Healing Time
- The American College of Physicians recommends that properly drained skin abscesses typically heal in 7-14 days, remaining open throughout this period while healing by secondary intention 1, 2
Factors Affecting Healing Time
- Complete and adequate drainage is the most critical factor for successful healing, more important than the use of antibiotics, according to the World Journal of Emergency Surgery 3
- Risk factors for recurrence, which can prolong the healing process, include inadequate drainage, loculations, horseshoe-shaped abscesses, and prolonged time from onset to incision 3
Wound Management After Drainage
Wound Packing
- The Infectious Diseases Society of America recommends against routine packing of the abscess cavity after drainage, as it is painful, costly, and does not improve healing 1, 4
- A Cochrane review found insufficient evidence to support the use of packing 3
- Simply covering the surgical site with a dry dressing is usually the easiest and most effective treatment 1
Wound Care
- The wound should be left open and allowed to heal by secondary intention, with regular dressing changes until the cavity is fully healed 2, 4, 3
- Primary closure with sutures is not recommended for simple abscesses 1
Indications for Antibiotics in Patients with Recurrent MRSA
When to Use Antibiotics
- The Centers for Disease Control and Prevention recommend that antibiotics are indicated in addition to drainage when there is: erythema or cellulitis extending >2-5 cm beyond the abscess margin, systemic signs of infection, or immunocompromised patients 1, 2, 5
- Antibiotics are also recommended for patients with multiple or rapidly progressing abscesses 6
Recommended Antibiotic Regimen
- For recurrent abscesses with possible MRSA, the recommended treatment is trimethoprim-sulfamethoxazole 160-320/800-1600 mg (1-2 double-strength tablets) twice daily for 5-10 days, according to the Clinical Infectious Diseases journal 5, 6
Important Warnings
- Cultures should always be obtained from the drained abscess to identify the pathogen and guide antibiotic selection, as recommended by the Infectious Diseases Society of America 5, 6
- Local underlying causes that perpetuate recurrence, such as pilonidal cysts, hidradenitis suppurativa, or foreign material, should be sought and addressed 5, 6
- Recurrence rates after drainage can be as high as 44% without adequate treatment, highlighting the importance of proper wound care and follow-up 3
- Aspiration with a needle is not effective (<10% success with MRSA) and is not recommended, according to the Clinical Infectious Diseases journal 1