Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 2/11/2026

Management of Severe Hypercholesterolemia in Patients Receiving Atypical Antipsychotics

Initial High‑Intensity Statin Therapy

Escalation with Ezetimibe

Further Escalation with PCSK9 Inhibitors

Risk‑Based LDL‑C Targets

Special Considerations for Metabolic Risk

Monitoring and Safety