Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 12/30/2025

Maximum Time Window for Thrombolytic Therapy in STEMI

Standard 0‑12‑Hour Window

Extended 12‑24‑Hour Window (Selected Patients)

Reperfusion Strategy Determined by PCI Availability

Pathophysiological Rationale for the 12‑Hour Limit

Common Clinical Pitfalls

Cardiogenic Shock Considerations