Treatment of Group B Strep Urinary Tract Infection with Cephalexin

Clinical Considerations

• For Group B streptococcal infections, treatment should be continued for the full prescribed duration to ensure complete eradication 1

Special Considerations

• In patients with penicillin allergy who are not at high risk for anaphylaxis, cephalexin remains an appropriate choice 2

Common Pitfalls to Avoid

• Underdosing or premature discontinuation of therapy may lead to treatment failure or recurrence 1
• Antimicrobial agents should not be used before the symptomatic phase to treat GBS colonization, as this is not effective in preventing disease and may cause adverse consequences 4
• Failure to consider local resistance patterns when selecting empiric therapy could lead to treatment failure 3

Monitoring and Follow-up

• No routine follow-up testing is required if symptoms resolve completely 3