Treatment of Mumps in Pregnancy

Primary Symptomatic Management

The American College of Obstetricians and Gynecologists recommends providing acetaminophen or NSAIDs for pain and fever control to manage fever, headache, and parotid gland pain in pregnant women with mumps 1
The American College of Obstetricians and Gynecologists suggests ensuring adequate hydration and fluid intake, as parotitis makes swallowing uncomfortable and painful in pregnant women with mumps 1
The American College of Obstetricians and Gynecologists advises recommending soft foods and avoidance of acidic foods that may stimulate salivary flow and worsen parotid pain in pregnant women with mumps 1

The Centers for Disease Control and Prevention recommends implementing droplet precautions immediately, as patients are contagious from 7 days before through 8 days after parotitis onset 1
The Centers for Disease Control and Prevention suggests isolating for 5 days after onset of parotitis to limit spread to susceptible contacts 1
The Centers for Disease Control and Prevention advises educating family members about transmission through respiratory droplets and direct contact with saliva 1

The American College of Obstetricians and Gynecologists recommends monitoring for aseptic meningitis, which occurs in 4-6% of cases, characterized by severe headache, neck stiffness, photophobia, or altered mental status in pregnant women with mumps 1
The American College of Obstetricians and Gynecologists suggests watching for signs of encephalitis, including seizures, paralysis, or cranial nerve palsies, which can cause permanent sequelae in pregnant women with mumps 1
The American College of Obstetricians and Gynecologists advises assessing for hearing loss, including sudden sensorineural deafness in pregnant women with mumps 1
The American College of Obstetricians and Gynecologists recommends monitoring for oophoritis, which can present with pelvic pain in pregnant women with mumps 1
The American College of Obstetricians and Gynecologists suggests watching for pancreatitis, characterized by severe abdominal pain, nausea, and vomiting in pregnant women with mumps 1

The American Academy of Neurology recommends initiating corticosteroid therapy promptly with prednisone 1-2 mg/kg/day for 5-7 days followed by a taper over 5-7 days to reduce inflammation and improve nerve function in patients with facial nerve inflammation due to mumps 1
The American Academy of Ophthalmology advises providing eye protection to prevent corneal damage in patients with facial weakness due to mumps 1
The American Academy of Neurology suggests reassuring patients that complete recovery occurs in approximately 70-80% of cases within 3-6 months 1

The Centers for Disease Control and Prevention states that mumps disease is generally self-limiting, with most patients recovering without intervention beyond supportive care 1
The Centers for Disease Control and Prevention notes that parotitis is not present in all cases—only 30-40% of mumps infections produce typical acute parotitis, while 15-20% are asymptomatic and up to 50% present with nonspecific or respiratory symptoms 1, 3
The Centers for Disease Control and Prevention advises that complications are more common and severe in adults than children, making age an important consideration in monitoring intensity 1
The Centers for Disease Control and Prevention recommends that the mumps vaccine is contraindicated during pregnancy due to theoretical risk of fetal harm from live-virus vaccine, though accidental vaccination has not been shown to cause maternal/fetal complications 2, 4
The Centers for Disease Control and Prevention states that there is no evidence that mumps causes congenital malformations, unlike rubella 2