Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/2/2025

Cefixime Dosing Guidelines

Standard Pediatric Dosing

  • The American Academy of Pediatrics recommends a single daily dose of 8 mg/kg of the oral suspension, which can be administered as 8 mg/kg once daily 1
  • The FDA-approved dosing for pediatric patients 6 months or older is 8 mg/kg/day of the oral suspension, which can be administered as 4 mg/kg every 12 hours 2

Specific Calculation for Pediatric Patients

  • For a 20.3 kg child, the total daily dose is 20.3 kg × 8 mg/kg = 162.4 mg/day (round to 162 mg), according to the Clinical Infectious Diseases guideline 2

Alternative Oral Cephalosporin Options

  • The Infectious Diseases Society of America recommends cefdinir, cefpodoxime, or ceftibuten as alternatives for beta-lactamase producing Haemophilus influenzae infections 1, 2