Risks and Recommendations for Antiepileptic Drugs During Pregnancy

Medication Use and Pregnancy

• For women with mild manifestations of conditions treated with carbamazepine, consider discontinuing therapy prior to or during pregnancy due to the fetal risks 1
• A comprehensive evaluation of risks and benefits should be conducted prior to conception when possible, considering the severity of the underlying condition and risks of untreated disease 2
• The American Academy of Neurology recommends evaluating the necessity of the medication for the specific condition being treated, and using the lowest effective dose of medication when treatment is necessary 1
• Consider switching to medications with better pregnancy safety profiles when possible and clinically appropriate 2