Liver Enzyme Recovery After Stopping Vandetanib

Monitoring and Follow-up

• The American Gastroenterological Association recommends checking liver enzymes within 1 week after stopping vandetanib to confirm the downward trend, and continue monitoring liver function tests every 1-2 weeks until significant improvement is observed, with more frequent monitoring for patients with more severe liver injury (grade 3-4) 1
• Consider using the new nadir values of liver enzymes as reference points rather than pre-treatment baseline levels for monitoring purposes 1