Safety of Mupirocin for Penile Infections

Indications and Safety Profile

Mupirocin is indicated for topical treatment of impetigo and other localized skin infections caused by susceptible strains of Staphylococcus aureus and Streptococcus pyogenes, according to the American Academy of Pediatrics 1

Mupirocin has excellent activity against Staphylococcus aureus (including MRSA) and Streptococcus species, which are common causes of skin infections, as reported by the American Academy of Pediatrics 1

For infections involving mucosal surfaces of the penis, alternative antimicrobial agents formulated for mucosal use may be more appropriate, as suggested by the Infectious Diseases Society of America 2
For skin abscesses, incision and drainage along with appropriate systemic antibiotics based on culture results is recommended, according to the American Academy of Pediatrics 1
For MRSA infections, treatment options include trimethoprim-sulfamethoxazole, doxycycline, or clindamycin for susceptible isolates, as recommended by the American Academy of Pediatrics 1