Fluconazole Treatment for Yeast Infections

Dosing Recommendations

The Infectious Diseases Society of America recommends a single 150 mg oral dose of fluconazole for uncomplicated vulvovaginal candidiasis 1
For severe acute vulvovaginal candidiasis, fluconazole 150 mg every 72 hours for a total of 2-3 doses is recommended 1
Initial induction therapy with 10-14 days of a topical agent or oral fluconazole, followed by maintenance therapy with fluconazole 150 mg weekly for 6 months, is recommended for recurrent vulvovaginal candidiasis 1

For symptomatic cystitis, fluconazole 200 mg (3 mg/kg) daily for 2 weeks is recommended 2, 3
For pyelonephritis, fluconazole 200-400 mg (3-6 mg/kg) daily for 2 weeks is recommended 2, 3
For high-risk patients undergoing urologic procedures, fluconazole 200-400 mg daily for several days before and after the procedure is recommended 3

Confirm diagnosis with clinical examination and wet mount/KOH preparation, then determine if infection is uncomplicated or complicated, and treat accordingly 1