Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/27/2025

Prevention and Control of Rat-Borne Diseases

Rodent Control Measures

  • The Centers for Disease Control and Prevention recommends keeping food and water covered and stored in rodent-proof containers to prevent rat infestations 1
  • Regular disposal of trash and garbage is advised to prevent rodent attraction 1
  • Eliminating clutter where rodents might nest is essential for rodent control 1
  • Using spring-loaded traps with peanut butter as bait is a recommended method for rodent control 1

Cleaning and Disinfection

  • The Centers for Disease Control and Prevention suggests wearing protective gloves, such as rubber, latex, vinyl, or nitrile, when cleaning rodent-contaminated areas 2, 3
  • Spraying rodent urine and droppings with disinfectant or chlorine solution before cleaning is recommended to prevent aerosol generation 2, 3
  • Avoiding vacuuming or sweeping until disinfection is complete is advised to prevent aerosol generation 2, 3
  • Using paper towels to pick up urine and droppings is recommended, followed by disinfection of all potentially contaminated surfaces 2, 3

Handling Dead Rodents

  • Wearing protective gloves is necessary when handling dead rodents to prevent exposure to diseases 4
  • In the western United States, using insect repellent containing DEET is recommended to prevent fleabites when handling dead rodents 4
  • Spraying dead rodents with disinfectant or chlorine solution is advised before disposal 4
  • Double-bagging rodent remains for disposal is recommended to prevent further contamination 4

Heavy Rodent Infestations

  • Ventilating closed buildings for at least 30 minutes before entering is recommended to prevent exposure to airborne pathogens 4
  • Wearing appropriate protective equipment, including coveralls, gloves, goggles, and respiratory protection, is necessary when dealing with heavy rodent infestations 4
  • Contacting local health authorities for guidance is recommended in cases of heavy rodent infestations 4