Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/7/2025

Management of Sore Gums and Canker Sores

Initial Clinical Assessment

  • The American College of Oral Medicine recommends documenting the duration of symptoms, as ulcers persisting beyond 2 weeks require more aggressive workup 1
  • A systematic visual inspection of the entire oral cavity should be performed to identify all affected areas 3
  • Identify and document sources of mechanical trauma such as ill-fitting dentures, fractured teeth, or sharp dental restorations that may be contributing to gingival irritation 2, 4
  • Assess ulcer morphology: recurrent aphthous ulcers typically present as well-demarcated, oval or round ulcers with white or yellow pseudomembrane and surrounding erythematous halo 1

First-Line Treatment Measures

  • Brush teeth twice daily using a small, ultra-soft-headed, rounded-end bristle toothbrush with prescription-strength fluoride toothpaste 5, 2
  • Rinse vigorously with bland rinse (1 teaspoon salt, 1 teaspoon baking soda in 4 cups water) at least 4 times daily 5, 2
  • Avoid commercial mouthwashes with alcohol base as they cause additional pain, irritation, and impair healing 5, 2

Laboratory Testing

  • Blood tests should be obtained before biopsy for ulcers that do not respond to 1-2 weeks of treatment or have duration exceeding 2 weeks 1
  • Required blood work includes complete blood count, coagulation studies, fasting blood glucose, HIV antibody, and syphilis serology 1

Topical Symptomatic Relief

  • Use only animal or plant-based oils such as beeswax, cocoa butter, and lanolin for lip lubrication 5
  • Avoid petroleum-based products as they promote mucosal dehydration and create an occlusive environment increasing secondary infection risk 5, 2

Elimination of Trauma Sources

  • Have dental team eliminate sources of mechanical trauma including ill-fitting dentures or fractured teeth 2, 4
  • Counsel patients to avoid conscious cheek biting or tongue thrusting against oral mucosa 4

Follow-Up and Escalation Criteria

  • Evaluate treatment response within 2 weeks 2
  • If no improvement is seen after 1-2 weeks of treatment, reevaluate for correct diagnosis and consider biopsy 1, 2

Common Clinical Pitfalls

  • Do not rely solely on clinical appearance for diagnosis, as many conditions can mimic aphthous ulcers including bullous diseases, infections, drug reactions, and malignancies 1
  • Chronic use of petroleum-based lip products creates an occlusive environment that increases infection risk 5, 2

REFERENCES

2

Management of Foreign Body Sensation in the Oral Cavity [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

3

Non-Pharmacological Treatment for Self-Inflicted Tongue Bite [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

4

Management of Linea Alba of the Buccal Mucosa [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025