Treatment of Hyperthyroidism with Methimazole

Clinical Application and Dosing

The goal of treatment is to maintain free T4 or Free Thyroxine Index (FTI) in the high-normal range using the lowest possible thioamide dosage, according to the American Academy of Family Physicians 1
Monitoring of free T4 or FTI every 2-4 weeks is recommended to adjust dosing appropriately, as suggested by the American Academy of Family Physicians 1
Beta-blockers may be used concurrently until thyroid hormone levels are reduced to manage symptoms, as recommended by the American Academy of Family Physicians and supported by the Journal of Clinical Oncology 1, 2

Potential adverse effects of Methimazole include agranulocytosis, hepatitis, vasculitis, and thrombocytopenia, as reported by the American Academy of Family Physicians 1